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Topic Sentence In A Research Paper
Monday, August 24, 2020
Your Not Fat, Just Big Boned. Essays - Obesity, Discrimination
Your Not Fat, Just Big Boned. Your Not Fat, Just Big Boned. Numerous individuals have heard the terms your not fat, simply enormous boned, well nurished, or maybe imposing. All things considered, as sombody of my age may state WHATEVER. Face it America were fat. I am discussing fat, the extra tire syndrom, or anyway you might want express it, yet were as yet fat. We are on the whole searching for a decent get slight quike sceam, you realize the one that takes no effert, and conceivable charming. At that point, again I'm reluctant to disapoint you, there isn't, nor will there ever be, however maybe it's easier than most figure it out. We Americans are fat for a few distinct reasons and they have close to nothing or nothing to do with our weight control plans or what we eat. Our obeasity starts when were youthful. You may have had guardians like mine, the guardians who said your not pardoned untill you eat everything on you plate, or maybe they commited a twofold phopa and said no desert untill your plate is cleared. What ever the case might be, a significant number of us are fat as a result of it. These expressions become latched onto our subconscious minds, and from that point on each time we take a seat at the table climate it be a great deal or a little we will uncontiously eat it untill our plate is spotless, or we are truly full. A basic answer for a basic issue, and goes like, this put less on your plate. A couple of approaches to atempt this are spread out your food on your plate, include not many veggies and enhancements cause it to give off an impression of being more than what it realy is. Another is drink an enormous glass of water before you start to eat, and maybe simply eat more slow. The entire thought behind this idea is to trick the brain. Our psyche discloses to us when we're ravenous not on the grounds that our stomach is vacant, but since it needs something or it figures it does, and by far most of the time being the later. The brain resembles any machine in being that we can program and train it for any funtion, all pending knowing how. So in this first technique we are straightforward reinvent it. As we develop more established different facters start to play a roll, and the greatest is our public activity. Our psyche can not consider eating so easly on the off chance that we have it on something different. In the teenager years is the point at which this turns out to be generally apparent. In the event that you review, the understudies that were engaged with most of funtions were not the fat youngsters. The fat youngsters were not included close to so a lot, sure they were presumably shy, and no uncertainty there were different elements included, yet it is all psychological somehow, and again it's all amatter of programing. Later on throughout everyday life, we become contiously mindful of our over weight issues, and this is incredible, however this is were the most concerning issue starts. Not exclusively does this issue influence our weight yet our life expectancy, and our life all in all. The issue passes by the notable name of pressure. I request that you take a gander at what number of live very much into their 80's. at that point inquire as to whether any of them weried about practicing good eating habits. Not that eating well is terrible as you may already know. The issue lies with the pressure of practicing good eating habits. At the point when most tear open that choclate bar they start to appreciate a joy of life, yet they'er before long reasoning thatb they will think twice about it, since some place a long the line we started to assotiate pleasuer with the possibility of gread, or that for reasons unknown we don't merit this delight, yet I diverge. The genuine tie among pressure and food are the cemical responses the reason in our psyches. Choclate creases to be the devals reward for ladies. Ladies have such an issue with choclate, in light of the fact that it discharges a similar compound in the mind that comes when they begin to look all starry eyed at, and they basicly experience passionate feelings for chochlate. men will in general have a similar impact with read meat. Food isn't the issue at everything except in actuality the response it has on our feelings. In any circumstance everything bubbles
Saturday, August 22, 2020
Son of the Revolution Essay Example
Child of the Revolution Essay Example Child of the Revolution Essay Child of the Revolution Essay A life account ââ¬Å"The Son of the Revolutionâ⬠by Liang Heng and Judith Shapiro is a surprising story that represents two many years of the financial, political and social circumstance in China between late 50s and 70s. The book grasps the hour of the Cultural Revolution, which comprised of different political developments, for example, The Hundred Flowers Movement, The Great Leap Forward, etc. The simultaneous nearness of the forceful superpowers like the Soviet Union and the USA on the global scene has significantly exacerbated the circumstance in China. As indicated by the examination of two political specialists it is proper to declare that: during the Cold War, China was the main significant nation that remained at the convergence of the two superpower camps, an objective of impact and ill will for both. (Nathan and Ross 13). In mid 1950s China involved a tremendous domain and was a nation that must be thought about, particularly by the two superpowers. China turned into an accomplice of the Soviet Union inside the system of shared socialist turn of events and collaboration. In 1953-57 various bargains of fellowship, participation, and common help were joined by China and the USSR. It has prompted the advancement of the Chinese business and an expansion in assembling limit. The Soviets were giving China a noteworthy number of specialists, logical developments, material and specialized premise. In the XXth century, Chinaââ¬â¢s pioneer Mao Zedong was unequivocally impacting the philosophy utilizing it as the most significant mean for molding the nationââ¬â¢s perspectives. In addition, being engaged with the showdown between the USA and the socialists, China joined the last getting a lot of benefit from the relationship than from some other organization previously. The USSR was providing China with nat ional security, supporting it monetarily as the Western nations built up a financial stop on the Chinese items and administrations. In this manner, the intensity of the Communist philosophy has reinforced and turned out to be considerably progressively pivotal for the eventual fate of the nation. The intensity of that political circumstance can be seen from the way that Liang Hengââ¬â¢s father being one of the principle bookââ¬â¢s characters has been a given devotee of Mao all through the story. His sonââ¬â¢s youth was permeated with ideological mottos guaranteeing youthful Liang Heng in the truth of life where he ought to be a ââ¬Å"Chairman Maos Good Little Boyâ⬠. Notwithstanding embarrassment, savage and unfair demeanor Liang Shan has encountered, he stayed a legitimate hireling of the socialism system and couldnââ¬â¢t turn off the street. From the start, Liang Heng stays under control as his dad requested him to act. He appreciates tuning in to Maoââ¬â¢s addresses, discussing it with the relatives and others. The distinctive case of youthful Hengââ¬â¢s pleasure and eagerness related with his forced political inclinations and accepts is delineated in the book when Mao shows up to Peking and gives a discourse outside. The crowed is so glad to watch t he main individual of the nation that some beginning expressing that they have contacted Maoââ¬â¢s hand. The frenzy holds onto individuals and they attempt to draw nearer to one another so as to even indirectly feel the soul of ââ¬Å"the Greatâ⬠. A while later, seeing the pioneer once more, Liang Heng considers Mao the reddest sun of his heart and enlightens everyone concerning his occurrence with the Chairman. (Liang and Shapiro 124). Clearly, the circumstance of common comprehension between two incredible states has become a terrible amazement for the USA that was put up close and personal with a global encounter. So as to play out a retaliatory blow, the last came into activity by requiring the Korean and the Vietnam War. As a result of the USSRââ¬â¢s exertion dissipating, China got some distance from its previous persuasive accomplice and propelled the arrangement of worldwide relationship fortifying. The break in the connections between Maoââ¬â¢s China and the Soviets occurred after Stalinââ¬â¢s passing. Mao Zedong inferred that the time had come to announce him a headquarter, therefore promptly positioning the USSR as a foe and a contender. All through the book ââ¬Å"Son of the Revolutionâ⬠the Chinese home arrangement is seriously impacting the Liang Hengââ¬â¢s character and his entire condition as he is attempting to fit in the framework with extraordinary enthusiasm. The socialist philosophy in China was such, that individuals had to have confidence in the ghastliness and bad dream of the capitalism.â The book depicts the multi-esteemed technique of the China specialists toward the customary individuals. On one hand, the legislative technique as per which private enterprise negatively affects virtues of the entire humanity is openly communicated, however then again similar authorities and their delegates take all real antagonistic belongings, for example, land, individual things, steers from their populace. It might be plainly seen in the discourse between Liang Hengââ¬â¢s father and Guo Lao-da â⬠a farmworker: What will I do? My ducks have bolstered me my entire life. Do they need us to starve to death to battle Capitalism? Quiet, murmured Father. They could victory your cerebrums for saying less. At that point he talked delicately with him until the fire freeloaded down extremely low. I was at that point sleeping in the kitchen when Guo Lao-da went out to murder the ducks. (Liang and Shapiro 211). Seeing every one of these difficulties and defying the imbalance, Heng communicates his feelings in one of the letters to his companion who is viewed as a foe. He addresses the accomplishment of the Cultural Revolution, he attempts to discover a response for being dealt with so unreasonably and tries to uncover the motivation behind why individuals have contributed such a great amount to the national thriving getting nothing consequently. The circumstance where Liang Heng, Liang Shan and others ended up was an ideal domain for dissatisfaction and self-underestimation. The focal point of the story lies in a huge number of the crushed lives that served loyally to the system however out of nowhere were back where theyââ¬â¢ve began. The general disaster of the period portrayed in the book is that the belief system glanced better in principle. That is when individuals would have liked to be similarly treated and to have equivalent rights and particular salaries. They were neither letha rgic nor stupid; they put forth a valiant effort to have a cheerful existence remaining absolutely gave to the pioneer and his delegates. Rather, their ways of life were brutal and abusive, loaded with surprising issues, consistent modesty and vulnerability. Every one of them were seeking after a solitary beam of expectation in the haziness of the real world. Looking for a superior life a large number of the Chinese moved to another prosperous nations. Liang Heng did likewise and was planning to return various years and become an observer of a countryââ¬â¢s financial, social and social turn of events. Sadly, it didnââ¬â¢t work out. Also, he has seen that the specialists were not urging individuals to uncover their gifts, aptitudes and information. Their strategy requested a similar congruity and system making a climate of balance. Be that as it may, the last was progressively connected to the balance of national handicap to create and make.
Sunday, July 19, 2020
DHgate
DHgate WHAT IS DHGATE?The CompanyDHgate is a Chinese ecommerce platform which focuses on business to business sales. The aim of this website is to create a connection between small and mid-sized businesses based in China and potential buyers worldwide. These potential buyers can purchases products manufactured in China from the website directly from the manufacturer. As with other Chinese ecommerce platforms, the website offers detailed customer support through email, telephone and chat services.The name is derived from the word Dunhuang which is a Chinese city in the Gansu province. In ancient times, the city was a strategic location along the Silk Road which connected China the rest of the world. The company draws on this comparison and positions itself as a modern day Silk Road, providing the same connection between China and the rest of the world.The products listed on the website include electronics, sports supplies, clothes, accessories and beauty products among others. The majority o f buyers for the website are located in North America and Europe. HistoryDiane WangThe company was created by Diane Wang in 2004. Wang remains the current CEO of the company. A well-known figure in China, she is often covered by the countryâs media. Prior to founding DHgate, she was among the people who created Joyo.com, now Amazon China. During her career she has served as the country marketing director for Cisco Systems China, managing China marketing communications. Her other credentials include Marketing Service Manager and Head of Business Development for Microsoft China for six years.Diana has received the âOutstanding Woman of Chinaâ and âOutstanding Woman of Beijingâ awards. These are two of the highest accolades received by professional women in China.She began her career as a lecturer at the TsingHua University in Beijing, China. Ambitious for more, she applied for a position in Microsoft China and was selected. Though the corporate culture was a bit of a shock f or her, she managed to stay on and went on to outperform all other sales teams. Though she faced class ceiling when it came to promotions and growth, she persevered and took each new supervisor as an opportunity to learn and grow. It paid off, with a promotion that made her the first professional executive to be promoted in the company from mainland China.After moving to Cisco, she co-founded Joyo.com and led the startup through the internet boom and downturn. The business grew and was eventually acquired by Amazon. In 2004, she created a new ecommerce platform by the name of DHgate. The company had 425 employees as of 2012 with 50 percent of them being female.The CompanyAs of 2011, the company is said to have close to 25 million listings of products from as many as 900,000 suppliers who are Chinese. There are also 4 million buyers registered from as many as 230 different countries. The companyâs quick growth landed it on the 2009 Deloitte list for Chinaâs Top 50 Fast Growing En terprises.The company had a strategic relationship with PayPal till 2012. Since then, PayPal is no longer an accepted means of payment on the website. The company works with China Construction Bank to provide a microloan service to those users who have good record on the website. The company also works with UPS and eBay.THE BUSINESS MODELThe website does not charge a membership fee from either buyer or seller. Instead, it charges only a commission as a percentage of successful transaction amounts. This percentage ranges from 3 percent to 10 percent. Though the website remains free for sellers, a special value added services feature called DHfactory has recently been added. Sellers can pay an annual fee to avail this service. The company is set to launch further exclusive services to compete better in the Chinese online wholesale market.Buyers and sellers are required to interact through the website. There is an escrow payment service that protects buyers and a customer service depar tment to help resolve disputes.The company is built to facilitate small and medium sized Chinese enterprises. Average order sizes remain small for this reason. The variety of items listed however, is not affected by the size of the businesses and categories of products include clothes, bags, shoes, sports items, toys, jewelry, electronics, mobile phones, musical instruments, car parts, video games and many more.DifferentiationDHgate differs from other Chinese ecommerce platforms by focusing on only smaller scale manufacturers and suppliers. In addition, the transactions and payments are through the website which offers some degree of trust and reliability for the buyers. The website offers benefits to small suppliers that have thus far been restricted to only larger and more business aware suppliers. These small suppliers are able to get quick and easy access to the global supply chain.LESSONS FROM THE DHGATE FOUNDERThe DHgate founder has overcome odds again and again to become one of the most respected and successful business women in China. Because of her experience with multinationals as well as startups, as well as her entrepreneurial venture, she has a lot to offer to potential entrepreneurs.6 Tips for Achieving Entrepreneurial GoalsDream Big: This is Wangâs number one prerequisite for any entrepreneur. She believes that the road to the fulfillment of any dream is full of adversity and the temptation to give up. If the dream is big enough and the belief in it strong enough, then these difficulties can be overcome and the goal achieved. She says, âThe original dream is the foundation that empowers you to stay focused whenever you feel lost.âMake Entrepreneurship a Lifestyle: According to Wang, no one can treat entrepreneurship as a part time endeavor. Instead, it needs to be a lifestyle change and choice which goes on to impact every aspect on your life. She believes that a person needs to be physically and psychologically strong to handle any challe nges that arise. As an employee of a company, one always has the option to leave the job if one is not challenged or happy. But as an entrepreneur, the option to give up or take a break is not available at all.Let go of Comfort Zones: When you are an entrepreneur, there is no chance of being able to stay within your comfort zone. There has to be a constant readiness to play any role that needs to be played and stretch yourself in often unexpected ways. Wang says that she was not always comfortable with public speaking. But when she became the public face of her company she had no choice but to practice, overcome anxiety and become a strong speaker. She says, âOver time, I realized it was an invaluable self-improvement process, and an opportunity to grow with the company.âDonât Look for Shortcuts: DHgate was created when the value of ecommerce was still not understood or recognized by most people in the country. To overcome this lack of awareness, Wang and her team made dozens of trips on trains, motorcycles and even donkey carts to get across the country and explain the benefits directly to the manufacturers. There is no magic pill and real work needs to be done to achieve success.Find Your Niche: Wang believes that it is important to narrow focus and find a niche to work within. It is not always possible to beat all competitors in all areas. Instead, a niche along with a unique selling point can help differentiate you from competitors and become the biggest fish in your pond.Lean on Others When Needed: Wang emphasizes the importance of staying outwardly focused as well. This includes getting to know people in the field but outside the company and build up a network. This network can then be leveraged to fill any gaps in the business. This can be done through a partnership with people or companies. Experienced investors can be identified and encouraged to invest in the business to help growth. Wang says, âThis allows you to remain focused on what you a re good at, and to unleash your potential to create something of significance.âTAKING PRECAUTIONSServices Offered by DHGATEThe website offers three services that can protect buyers from counterfeits or scams.Seller Feedback: This is a rating given to each seller by various buyers. A higher rating means a higher degree of reliability given previous performance. The comments section gives more detail about the ease of doing business, seller attitude, credibility, reliability and support.Escrow Service: The escrow service sees DHgate act as a third party that collects and holds payment till the merchandise is shipped and received. If the buyer accepts the merchandise, then the payment is released by the escrow service.Dispute Process: When any disputes do occur, there is a dispute resolution process that tracks, manages and resolves disputes as quickly as possible with DHgate acting as a neutral and impartial mediator. Scams and SpeculationAs mentioned previously, there is not a lot of information available on this ecommerce platform. Though some of the information that is available is positive and encouraging, there is also a lot of confusion and many bad reviews on different websites. This lack of complete information means that any attempt to do business through DHgate should be undertaken after careful consideration, research and initial orders should be smaller amounts so as to find reliable suppliers for longer term commitments. There is also a danger of counterfeits and badly made items which again means a loss of revenue if investment is made in purchasing them.[slideshare id=30297007doc=dhgatescam-140122061325-phpapp02]Common ComplaintsSome of the negative customer experiences from DHgate include:Clothes: The most common issue that buyers face when buying clothes from the website are materials, fitting and delivery time. Most reviewers have felt that the items are delivered later than promised, often missing important occasions for which they were orde red. Others have found the items to be ill-fitting even though specific measurements had been provided. Still others found design mismatch from promised items as well as use of inferior quality materials.Electronics: Items are often received in battered conditions and will not work when turned on. Often they turn out to be non-working imitations. Some are sent to be exchanged and the seller disappears without replacing the item.Understanding Complaints: Users often find it difficult to communicate with both suppliers and DHgate employees themselves. DHgate is often accused of siding only with the supplier and not making an effort to understand the nature of the problem.Items Different from Listed Ones: A common complaint is when items delivered are drastically different from those shown on the website. In several such cases, the supplier becomes impossible to reach, does not respond to queries and the payment is released as the item has been delivered according to DHgate escrow rule s.Extremely High Shipping Costs: Some sellers will charge extremely high shipping costs as a way to offset the low prices on offer. It is a good idea to check all shipping charges before finalizing an order.ScamsThe most common scam found listed on the various review websites is when the seller sends an empty envelope to the wrong address deliberately. The item appears as delivered and the escrow service releases payment. In reality, the item is never shipped and never received by the customer.The other type of scam is basic counterfeit products. The supplier claims to sell originals at significantly lower prices than the original. These turn out to be counterfeits almost all the time.DHGATE SUCCESS STORIES © DHgateDHgate is a Chinese ecommerce platform for wholesale items sold by small and medium sized manufacturers and retailers. In this article, we will look at, 1) what is DHgate?, 2) the business model, 3) lessons from the DHgate founder, 4) taking precautions, and 5) DHgate success stories.WHAT IS DHGATE?The CompanyDHgate is a Chinese ecommerce platform which focuses on business to business sales. The aim of this website is to create a connection between small and mid-sized businesses based in China and potential buyers worldwide. These potential buyers can purchases products manufactured in China from the website directly from the manufacturer. As with other Chinese ecommerce platforms, the website offers detailed customer support through email, telephone and chat services.The name is derived from the word Dunhuang which is a Chinese city in the Gansu province. In ancient times, the city was a strategic location along the Silk Road which connected China the rest of the world. The company draws on this comparison and positions itself as a modern day Silk Road, providing the same connection between China and the rest of the world.The products listed on the website include electronics, sports supplies, clothes, accessories and beauty products among others. The majority of buyers for the website are located in North America and Europe. HistoryDiane WangThe company was created by Diane Wang in 2004. Wang remains the current CEO of the company. A well-known figure in China, she is often covered by the countryâs media. Prior to founding DHgate, she was among the people who created Joyo.com, now Amazon China. During her career she has served as the country marketing director for Cisco Systems China, managing China marketing communications. Her other credentials include Marketing Service Manager and Head of Business Development for Microsoft China for six years.Diana has received the âOutstanding Woman of Chinaâ and âOutstanding Woman of Beijingâ awards. T hese are two of the highest accolades received by professional women in China.She began her career as a lecturer at the TsingHua University in Beijing, China. Ambitious for more, she applied for a position in Microsoft China and was selected. Though the corporate culture was a bit of a shock for her, she managed to stay on and went on to outperform all other sales teams. Though she faced class ceiling when it came to promotions and growth, she persevered and took each new supervisor as an opportunity to learn and grow. It paid off, with a promotion that made her the first professional executive to be promoted in the company from mainland China.After moving to Cisco, she co-founded Joyo.com and led the startup through the internet boom and downturn. The business grew and was eventually acquired by Amazon. In 2004, she created a new ecommerce platform by the name of DHgate. The company had 425 employees as of 2012 with 50 percent of them being female.The CompanyAs of 2011, the company is said to have close to 25 million listings of products from as many as 900,000 suppliers who are Chinese. There are also 4 million buyers registered from as many as 230 different countries. The companyâs quick growth landed it on the 2009 Deloitte list for Chinaâs Top 50 Fast Growing Enterprises.The company had a strategic relationship with PayPal till 2012. Since then, PayPal is no longer an accepted means of payment on the website. The company works with China Construction Bank to provide a microloan service to those users who have good record on the website. The company also works with UPS and eBay.THE BUSINESS MODELThe website does not charge a membership fee from either buyer or seller. Instead, it charges only a commission as a percentage of successful transaction amounts. This percentage ranges from 3 percent to 10 percent. Though the website remains free for sellers, a special value added services feature called DHfactory has recently been added. Sellers can pay an an nual fee to avail this service. The company is set to launch further exclusive services to compete better in the Chinese online wholesale market.Buyers and sellers are required to interact through the website. There is an escrow payment service that protects buyers and a customer service department to help resolve disputes.The company is built to facilitate small and medium sized Chinese enterprises. Average order sizes remain small for this reason. The variety of items listed however, is not affected by the size of the businesses and categories of products include clothes, bags, shoes, sports items, toys, jewelry, electronics, mobile phones, musical instruments, car parts, video games and many more.DifferentiationDHgate differs from other Chinese ecommerce platforms by focusing on only smaller scale manufacturers and suppliers. In addition, the transactions and payments are through the website which offers some degree of trust and reliability for the buyers. The website offers bene fits to small suppliers that have thus far been restricted to only larger and more business aware suppliers. These small suppliers are able to get quick and easy access to the global supply chain.LESSONS FROM THE DHGATE FOUNDERThe DHgate founder has overcome odds again and again to become one of the most respected and successful business women in China. Because of her experience with multinationals as well as startups, as well as her entrepreneurial venture, she has a lot to offer to potential entrepreneurs.6 Tips for Achieving Entrepreneurial GoalsDream Big: This is Wangâs number one prerequisite for any entrepreneur. She believes that the road to the fulfillment of any dream is full of adversity and the temptation to give up. If the dream is big enough and the belief in it strong enough, then these difficulties can be overcome and the goal achieved. She says, âThe original dream is the foundation that empowers you to stay focused whenever you feel lost.âMake Entrepreneurship a Lifestyle: According to Wang, no one can treat entrepreneurship as a part time endeavor. Instead, it needs to be a lifestyle change and choice which goes on to impact every aspect on your life. She believes that a person needs to be physically and psychologically strong to handle any challenges that arise. As an employee of a company, one always has the option to leave the job if one is not challenged or happy. But as an entrepreneur, the option to give up or take a break is not available at all.Let go of Comfort Zones: When you are an entrepreneur, there is no chance of being able to stay within your comfort zone. There has to be a constant readiness to play any role that needs to be played and stretch yourself in often unexpected ways. Wang says that she was not always comfortable with public speaking. But when she became the public face of her company she had no choice but to practice, overcome anxiety and become a strong speaker. She says, âOver time, I realized it was an i nvaluable self-improvement process, and an opportunity to grow with the company.âDonât Look for Shortcuts: DHgate was created when the value of ecommerce was still not understood or recognized by most people in the country. To overcome this lack of awareness, Wang and her team made dozens of trips on trains, motorcycles and even donkey carts to get across the country and explain the benefits directly to the manufacturers. There is no magic pill and real work needs to be done to achieve success.Find Your Niche: Wang believes that it is important to narrow focus and find a niche to work within. It is not always possible to beat all competitors in all areas. Instead, a niche along with a unique selling point can help differentiate you from competitors and become the biggest fish in your pond.Lean on Others When Needed: Wang emphasizes the importance of staying outwardly focused as well. This includes getting to know people in the field but outside the company and build up a network . This network can then be leveraged to fill any gaps in the business. This can be done through a partnership with people or companies. Experienced investors can be identified and encouraged to invest in the business to help growth. Wang says, âThis allows you to remain focused on what you are good at, and to unleash your potential to create something of significance.âTAKING PRECAUTIONSServices Offered by DHGATEThe website offers three services that can protect buyers from counterfeits or scams.Seller Feedback: This is a rating given to each seller by various buyers. A higher rating means a higher degree of reliability given previous performance. The comments section gives more detail about the ease of doing business, seller attitude, credibility, reliability and support.Escrow Service: The escrow service sees DHgate act as a third party that collects and holds payment till the merchandise is shipped and received. If the buyer accepts the merchandise, then the payment is release d by the escrow service.Dispute Process: When any disputes do occur, there is a dispute resolution process that tracks, manages and resolves disputes as quickly as possible with DHgate acting as a neutral and impartial mediator. Scams and SpeculationAs mentioned previously, there is not a lot of information available on this ecommerce platform. Though some of the information that is available is positive and encouraging, there is also a lot of confusion and many bad reviews on different websites. This lack of complete information means that any attempt to do business through DHgate should be undertaken after careful consideration, research and initial orders should be smaller amounts so as to find reliable suppliers for longer term commitments. There is also a danger of counterfeits and badly made items which again means a loss of revenue if investment is made in purchasing them.[slideshare id=30297007doc=dhgatescam-140122061325-phpapp02]Common ComplaintsSome of the negative custome r experiences from DHgate include:Clothes: The most common issue that buyers face when buying clothes from the website are materials, fitting and delivery time. Most reviewers have felt that the items are delivered later than promised, often missing important occasions for which they were ordered. Others have found the items to be ill-fitting even though specific measurements had been provided. Still others found design mismatch from promised items as well as use of inferior quality materials.Electronics: Items are often received in battered conditions and will not work when turned on. Often they turn out to be non-working imitations. Some are sent to be exchanged and the seller disappears without replacing the item.Understanding Complaints: Users often find it difficult to communicate with both suppliers and DHgate employees themselves. DHgate is often accused of siding only with the supplier and not making an effort to understand the nature of the problem.Items Different from List ed Ones: A common complaint is when items delivered are drastically different from those shown on the website. In several such cases, the supplier becomes impossible to reach, does not respond to queries and the payment is released as the item has been delivered according to DHgate escrow rules.Extremely High Shipping Costs: Some sellers will charge extremely high shipping costs as a way to offset the low prices on offer. It is a good idea to check all shipping charges before finalizing an order.ScamsThe most common scam found listed on the various review websites is when the seller sends an empty envelope to the wrong address deliberately. The item appears as delivered and the escrow service releases payment. In reality, the item is never shipped and never received by the customer.The other type of scam is basic counterfeit products. The supplier claims to sell originals at significantly lower prices than the original. These turn out to be counterfeits almost all the time.DHGATE SU CCESS STORIESAccording to the DHgate founder, there are many success stories from sellers who have used the platform to break barriers and achieve success. She mentions a young Chinese woman from a poor background who sold clothes through the website and eventually made enough money to move to Paris and study fashion design. There are also many stories of middle-aged women with children who have left home, who have built up businesses by selling products from home.However, because of the predominantly small scale nature of Chinese sellers that list on DHgate, there is very little direct information available about these sellers and their success stories. Instead, there are many stories of people or other small businesses in different parts of the world who buy from these Chinese sellers and successfully run their own businesses based on these products. Some of these stories include:William Daniel â" USAWilliam began by scoping out several websites for products and prices before dec iding to try out DHgate with a small electronics purchase. It was delivered on time and he was able to sell it for a profit. He continued to purchase from DHgate and sell onwards eventually growing his business enough to hire employees and continue to grow. He suggests researching the marketplace thoroughly before deciding to buy. He also suggests checking out the seller completely through ratings and conversations over email, chat or phone before establishing any relationship. If all else fails, he counts on the DHgate escrow service and the customer service team for support.Martin Flynn â" USAMartin uses DHgate to purchase cell phone related items and accessories to sell via his own online retail business. He now relies on DHgate as his only source of supply. He finds their prices extremely competitive and is happy with reliability of service.Carlucho Sabal â" USASabal runs a small company that conducts business in Venezuela. The company was unable to raise the substantial funds required to import products in bulk via a container from China. They decided to go small instead and purchase from different wholesale websites online. Through some of these, the items received were either damaged or got lost in transit. At this point they discovered DHgate. There were some initial issues before they understood and started making use of the seller feedback system. Once this was sorted out, Sabalâs company was in a position to select reliable sellers and slowly grow their own business.Timur Hassan â" UKTimur heard about DHgate and after preliminary research, decided to give the service a try. He created an online store and started listing items that he purchased from DHgate. After experimenting for two months, he decided to establish a relationship with one of the sellers. This seller was reliable and shipped sealed, good quality products as listed on the website. Shipping was quick and any damaged items were replaced easily. He is especially happy with the DHgat e escrow service which holds the buyerâs money until the item is delivered. He manages to resolve any issues with support from the DHgate live chat service.Image credit: DHgate.
Thursday, May 21, 2020
Whole Foods - 1021 Words
Whole Foods Market in 2010 Core Values and Strategy Wilmington University Name: Whitney Newman Date 1/13/13 Overview: Provide a brief overview of the company. Include such details as its history, present day situation, and any other pertinent information you think is helpful in understanding the company (points 5) * Whole Foods Market was founded in 1980 working with natural and healthy foods in Austin, Texas; itââ¬â¢s one of the worldââ¬â¢s largest of natural and organic foods supermarkets. In 2009, the sales total $8 billion and had 289 stores in the U.S. The Whole Foods Market plans to come up with strategies to help improve the company but to do so understanding the core values plays a major role in the companyââ¬â¢s planning. Theâ⬠¦show more contentâ⬠¦2. Is Whole Foodsââ¬â¢ strategy well matched to market conditions in the food retailing industry (one of the criteria for a winning strategy discussed in Chapter 1)? (points 10) * Yes, Whole Foodsââ¬â¢ strategy is well matched to the market conditions. Their product line strategy is focused on providing natural, o rganic, and gourmet food and nonfood items to their customers. Whole Foods is recognized by the USDA as being a Certified Organic grocer by Quality Assurance International. This means that all their products are grown organically; the products are grown without the usage of pesticides, fertilizers, bioengineered, growth hormones, or antibiotics. 3. Do you think John Mackey has a good strategic vision for Whole Foods? Why or why not? What do you like/dislike about the companyââ¬â¢s mission/vision ââ¬Å"Whole Foods, Whole People, Whole Planetâ⬠that is set forth in case Exhibit 1? Do the mission/vision and the core values underlying it (case Exhibit 3) really matter at this company or are they just nice words and cosmetic window dressing? Explain. (points 20) * Yes I do believe that John Mackey has a great strategic vision. Now that the organic food market is a fast growing market in which he had gotten into this market segment at the right time and knew what he had visions on doing. What I like about the companyââ¬â¢s mission/vision statement ââ¬Å"Whole Foods, Whole People, Whole Planetâ⬠is because its all about a healthier world. EspeciallyShow MoreRelatedWhole Foods : The Whole Food Markets Essay1369 Words à |à 6 Pagesââ¬Å"Whole Food Marketsâ⬠Week #6 If you were to ask people if they enjoy going to work on Monday, I am sure most of them would give you a funny look, and say ââ¬Å"Noâ⬠. Americans dislike of their jobs is very evident. To see the magnitude of this just look on social media. On Fridays, there are vast amounts of thank god itââ¬â¢s Friday (TGIF) memes indicating how happy they are that they are done with work for the week. Many American simply do not enjoy working. However, a select few actually do. They enjoyRead MoreWhole Foods955 Words à |à 4 PagesStrategy for Whole Foods Market Current Strategic Issues 1. How does Whole Foods sustain positive growth in sales? 2. How does Whole Foods cope with the downturn in the economy? 3. How does Whole Foods achieve sustainable competitive advantage? Rationale for Issues One of Whole Foods main strategic issues is how it should sustain positive growth in sales. Sales growth in 2008 was 0.8%, compared to sales growth increase of 8.2% in 2007. However, much of these low sales growth figuresRead MoreWhole Foods Essay990 Words à |à 4 PagesWhole Foods 1. Using the ABC model of an attitude, analyze what John Mackeyââ¬â¢s online comments about Wild Oats reveal about his attitudes. The Affect of Mackeyââ¬â¢s attitude can be seen in his statement to Perry Odak, the owner of Wild Oats, stating that ââ¬Å"Iââ¬â¢m going to destroy youâ⬠. The Affects can also be seen in Rahodebââ¬â¢s online posted when he stated that ââ¬Å"[Wild Oats management] clearly doesnââ¬â¢t know what it is doing. It has to future and no value. The verbal statement about Mackeyââ¬â¢s feelingsRead MoreWhole Foods1871 Words à |à 8 Pages1. (a) Whole Foods operates in the organic, or natural and specialty foods retail industry. Leading the industry, Whole Foods Market is the world s most successful natural foods grocery chain. Having recently acquired one of its main competitors, Wild Oats Market, Whole Foods currently competes with two other large grocery chainsÃâ"Kroger and Trader Joe s. The company also acquired Amrion, a company specializing in nutraceuticals (natural supplements with pharmaceutical-type benefits), creatingRead MoreWhole Foods Case980 Words à |à 4 PagesWhole Foods Market Case Whole Foods Market has evolved into one of the largest retailers of natural and organic foods. This company s rapid growth and market success has to do with being a mission-driven company. Whole Foods is highly selective about what they sell and are dedicated to their core values. Whole Food s integrated strategy consists of growth, differentiation, merchandising, and customer service. This strategic plan was aimed at expanding its operations to offer high quality andRead MoreMarketing Plan For Whole Foods1429 Words à |à 6 Pages Grocery shopping has become more diversified than ever before. Whole Foods Market and Trader Joeââ¬â¢s have become household names in the consumer arena. Markets such as Roots, and Common Market are also in the game even though they operate on a smaller scale. Despite comparable size in terms of locations, each storeââ¬â¢s growth has operated using a very different model. As Whole Foods has increased the number of retail centers that it operates, it has suffered accompanying growing pains in the distributionRead MoreWhole Foods Market Inc.1231 Words à |à 5 PagesINDUSTRY EVOLUTION Whole Foods Market Inc. is a service provider in the grocery industry, which report in the US economy under the North American Industry Classification System NAICS 42441, General-line groceries merchants wholesalers, by the time the company started operations in 1980 supermarkets had a history of 51 years. Supermarkets unlike other type of retail is considered truly American in origin, self service grocery stores are traced back to 1912 in Memphis Tennessee, and it was in 1930Read MoreWhole Foods Strategy1168 Words à |à 5 PagesThe company I will be presenting is Whole Foods, case number seven. Whole Foods is a supermarket chain based in Austin, Texas which emphasizes natural and organic products. As of September 2009[update], the company operates 302 stores: 291 stores in 38 U.S. states and the District of Columbia; six stores in Canada; and five stores in the United Kingdom. External assessment: There are over one hundred thousand grocery stores in the United States, with a wide variety of types. Stores range fromRead MoreWhole Foods Markets1582 Words à |à 7 Pagespaper examines the published case study Whole Foods Markets, 2005: Will There Be Enough Organic Food to Satisfy the Growing Demand? (Hitt, Ireland and Hoskisson, 2007, p. C534). Although the published study addresses numerous aspects of Whole Foods Marketââ¬â¢s business as a leading international retailer of ââ¬Å"naturalâ⬠organic foods, the analysis provided herein is focused on Whole Foods Marketââ¬â¢s ability to meet future growth demands. This paper explores Whole Foods Marketââ¬â¢s basic internal environmentRead MoreWhole Foods Market1309 Words à |à 6 Pages(i) Environmental Analysis ââ¬â External Opportunities and Threats The demographic, economic and the socio-cultural segments would be the most relevant segments to Whole Foods Market. These segments have a direct impact on the profitability, sustainability and survivability of Whole Foods Market, and the organic food industry. The relevance of the demographic segment stems from the fact that the age structure, income distribution and population size are important factors which will influence the demand
Wednesday, May 6, 2020
Communist Party And Anti Corruption - 1158 Words
On April 17, 1989, thousands of student protesters flooded Tiananmen Square, Beijing, to mourn Hu Yaobangââ¬â¢s death. Yaobang was the former General Secretary of the Communist Party and also served as a symbol of political reform and anti-corruption. The students asked the government to end corruption and to give political and economic reform. Demonstrations spread to different cities, with workers joining in. They complained about money and housing issues. The spread of the demonstrations concerned Party leaders, who thought there was going to be rebellion from the protesters. Li Peng, who ranked second in the Party, believed that they should ââ¬Å"nip it in the bud,â⬠while Party General Secretary Zhao Ziyang thought that Yaobangââ¬â¢s memorialâ⬠¦show more contentâ⬠¦All this does is help demonstrations spread. At this point, foreign coverage of the demonstrations is commonplace, but Party members cannot agree on how to handle the situation. With students going back to their classes, the protesters didnââ¬â¢t have any real leadership. Different factions did different things. Tension arose in the Communist Party while preparing for Soviet Party Secretary Mikhail Gorbachevââ¬â¢s trip to Beijing. Xiaoping wanted to solve the protester situation peacefully, but at the same time, he wanted them out of the Square for Gorbachevââ¬â¢s arrival. However, this would not be the case. On May 13, over 100 students in Tiananmen Square started a hunger strike in hopes for talks with the leaders of the Communist Party, knowing Gorbachev would arrive shortly. On May 15, Gorbachev arrived in Beijing. He was there for the first ever Sino-Soviet summit since 1959, 30 years prior. Unfortunately for him, the strike made plans for him welcomed in the Square be canceled. By the day after he arrived, there were at least 3,000 people that joined the strike, which was humiliating to Gorbachev. While this was happening, Zhao and Peng kept their respective stances; Zhao believed they should listen to the people and make reforms, while Peng maintained that the protesters were no good and that they were aiming to overthrow the Party. Xiaoping ignored
Dabur Brand Revie Free Essays
The brand name Dabur is derived from the words ââ¬ËDaââ¬â¢ for ââ¬ËDaktarââ¬â¢ or ââ¬ËDoctorââ¬â¢ and ââ¬Ëburââ¬â¢ from Burman. From those humble beginnings, the company has grown into Indiaââ¬â¢s leading manufacturer of consumer healthcare, personal care and food products. Over its 125 years of existence, the Dabur brand has stood for goodness through a natural lifestyle. We will write a custom essay sample on Dabur Brand Revie or any similar topic only for you Order Now An umbrella name for a variety of products, ranging from hair care to honey, Dabur has consistently ranked among Indiaââ¬â¢s top brands. Its brands are built on the foundation of trust that a Dabur offering will never cause anyone slightest of harm. The trust levels that this brand enjoys are phenomenally high. Dabur had a turnover of approximately US$ 750 Million (Rs. 3390. 9 Crore FY 09-10) ;amp; Market Capitalisation of over US$ 3. 5 Billion (Rs 15500 Crore), Ner income of : (INR) 425 Crore (2008-09)with brands like Dabur Amla, Dabur Chyawanprash, Vatika, Hajmola and Real. The company has kept an eye on new generations of customers with a range of products that cater to a modern lifestyle, while managing not to alienate earlier generations of loyal customers. The companyââ¬â¢s growth rate rose from 10% to 40% Dabur Foods, a subsidiary of Dabur India is expecting to grow at 25%. Its brands of juices, namely, Real and Active, together make it the market leader in the Fruit Juice Category Value: Mass market value For money The brand trunaroundâ⬠why? Overall slow down in FMCG Stiff competition To target young india ââ¬â largest consumer Modernize old brand equity-ââ¬Å" intangible assetâ⬠Dabur also has reinvented the mother logo Enter new category; innovate offerings Repositioning as FMCG company Moved away from Umbrella branding strategy Retaining Dabur as corporate brand identity Daburââ¬â¢s New Brand Architecture 5 Power Brands Umbrella brand for juice and other foods; aimed at p market consumer Product to be launched is Lemon Juice: Branded fruit beverage market in India is estimated to be worth Rs. 1,200 crore (nectars, drinks and juices combined) The fruit drink market Juice accounts 30%,Nectar:10%, Fruit drinks:60% COMPETITIVE ANALYSIS Pepsi co: Nimbooz has grown 29% Coca Cola : Minute Maid Nimbu Fresh- pulp based drink Parle : LMN this has grown 30% Market size of Lemon Juice in India in Organized sector: The unpackaged nimbu paani market in India is very large; to put it in perspective, it is twice the size of the total carbonated soft drinks industry. Indiaââ¬â¢s Parle Agro, the name behind the LMN brand which launched a year ago, has outperformed the market growing 30 per cent. Of the 600m-case juice market, lemon juice drinks have a 44 per cent share. According to an industry report 120bn litres of beverages are consumed annually in India with 55 per cent of sales of Indian soft drinks during the summer months of March to May, and companies are keen to maximise growth in this season. If next yearââ¬â¢s summer is as hot as this one, a nimbu paani drink or three will definitely be in order Target market: 1) Primary and secondary market SEC A and SEC B * Recreational * Fitness * Health Lifestyle * Sports Primary Market: * Teens ââ¬â More experimental * Youth ââ¬â Experimental and more buying power Working People who travels a lot * Secondary Market Secondary market: Travel Industry ââ¬â Airlines, Railways and Local Transport Systems ,Recreational ââ¬â Movie Theatres, Malls, Amusement Parks, school, collages, hotels, restaurants Market Segmentation: * Metropolitan Cities, major cities of the states, and towns. * Density of Area: Urban, Semi-urban, Rural. Climate: Tropical * Age ââ¬â 8 and above * Users perceive Lemon juice as a healthy drink. * Users drink fruit juice as a refreshing alternative to carbonated drinks. Users willingly spend on products related to health and lifestyle. Users enjoy Lemon juice not only as a means of healthy life, but as an intrinsically enjoyable Marketing strategy of Dabur: Dabur should reinforce the authentic ââ¬Å"homemadeâ⬠taste through aggressive marketing campaigns and have tried to appeal to the increasingly health-conscious Indian consumer by making them without artificial ingredients. Product Type: lomon Juice Features: Lemon Juice is a 100 percent Lemon juice which will be produced and marketed by the Dabur ltd. Brand Name: Lemon Juice Product Life Cycle: Our product lie in introduction period Low sales * High costs per customer * Negative profits * Innovator customers * Few competitors Objective: to create awareness and trial * Offer a basic product * Price at cost-plus * Selective distribution * Awareness ââ¬â dealers and early adopters * Induce trial via heavy sales promotion * Place Distribution Channel Product location availability Modes of transportation * Pricing Provide Lucrative discounts, deals and schemes Adopt sales oriented objective Have one price policy Price@ 8 Rs/ 200Ml * Promotion Promotional Tactics Provide free samples in the market for the brand awareness Advertising: To our target audience by using the message showing a glass full of Lemon juice ââ¬Å"Drink this much every day ââ¬Å" Tie up promotional strategy with: PVR, In film advertising Hero Honda: Hero Honda Motors Limited, based in Delhi, India is a joint venture between the Hero Group of India and Honda of Japan[2][3] It has been referred to as the worldââ¬â¢s biggest manufacturer of 2-wheeled motorized vehicles since 2001, when it produced 1. 3 million motorbikes in a single year. During the fiscal year 2008-09, the company has sold 3. 28 million bikes and the net profit of the company stood at Rs. 1281. 7 crore, up 32% from the previous fiscal year. verification needed][3] Hero Honda has been the largest two wheeler company in the world for nine consecutive years. The company had a market share of 41. 35% in the year 2008-2009 and over a 25 year span it has crossed the 15 million unit milestone. Hero Honda sells more two wheelers than the second, third and fourth placed two-wheeler companies put together. [4] The companyââ¬â¢s most popular model is the Hero Honda Splendor, which is the worldââ¬â¢s largest-selling motorcycle, selling more than one million units per year Heroâ⬠is the brand name used by the Munjal brothers for their flagship company Hero Cycles Ltd. A joint venture between the Hero Group and Honda Motor Company was established in 1984 as the Hero Honda company,India. During the 1980s, the company introduced motorcycles that were popular in India for their fuel economy and low cost. A popular advertising campaign based on the slogan ââ¬ËFill it ââ¬â Shut it ââ¬â Forget itââ¬â¢ that emphasised the motorcycleââ¬â¢s fuel efficiency helped the company grow at a double-digit pace since inception. Hero Honda has three manufacturing facilities based at Dharuhera and Gurgaon in Haryana and at Haridwar in Uttarakhand. These plants together are capable of churning out 3. 9 million bikes per year. [citation needed] Hero Hondaââ¬â¢s has a large sales and service network with over 3,000 dealerships and service points across India. Hero Hondaââ¬â¢s customer loyalty program,[clarification needed] the Hero Honda Passport Program, claims to be one of the largest programs of its kind in the world with over 3 million members Launch of New Prodcut: Honda Cart: A three Wheeler Cart will be a . 75 ton truck in the commercial vehicle segment which is dominated by large trucks. It can be called Indiaââ¬â¢s next generation mini truck . The sub one ton loads were transported by the three wheeler goods carriers. Although the quality and performance of these three wheelers are less than desirable there was still huge demand for these vehicles. It is this market where TATA Ace is the only leading competitor . It is the transportation at the â⬠last mileâ⬠market that Ace has captured. Honda Cart will have all the qualities of a winner. It will be cute, the engine would be good interms of mileage and performance, the comfort factor can very much there and more over it is a Truck and not an Auto. Priced competitively at 2. 00 lakh to 2. 20 lakh, which is below Ace is a value proposition that no one can refuse. The brand will launched at a point where there was a need for transportation of good speedily and conveniently and in a cost effective manner. Need for the Honda Cart: Honda Cart will be cost-effective means for local transport of small cargo in the long run. Previously, customers had to incur additional charges by renting vehicles with a much larger payload for small cargo movements. Due to pradhan mantri gramin sadak yojana , Road onnectivity is expected to greatly improve in rural areas ?It is envisaged that higher tonnages vehicles will be not allowed in cities ?In both the cases, all last mile distributing will be covered by large vehicles ?The exciting production in this category is cumbersome , coupled with safety, pollution ;amp; comfort etc.. issues Market Research : To understand the potential customer better. It found that there were two types of customers fo r Honda Cart : cost sensitive customers, and others who valued return on investment (ROI). The company targeted ROI customers who were willing to pay a higher price but wanted low operating costs. Comparative analysis :The Honda Cart would provide excellent economy with oil change required only for every 10,000 km when compared to three wheelers which required it for every 2,500 km. Evne TATA ACE required at every 9,000KM. The vehicle traveled at a top speed of 70 km per hour and had a mileage of 20 km per liter with a high payload capacity in compare to TATA ACE which has speed of 65 km per hour and 18km per liter as mileage. This enabled the owners to make more trips in less time. Bajaj Auto, Force Motors, Eicher, Piaggio and Ashok Leyland are very much on their way to entering the one-ton four-wheeler space. â⬠The official further added, ââ¬Å"Players like Eicher and Swaraj Mazda, which are already present in the 1. 5-ton truck space, will now shift their focus to one ton. â⬠Product: Honda Cart. PLC- Entry stage. Brand Name: Honda Cart Price: 2. 00Lakh-2. 20Lakhs Place : Tier II and III cities. Rural and semi urban. Promotion: The company could offer a range of additional accessories such as vehicle protection system, music systems and even Ganesha idols. Apart from the hygiene quality Honda will also look at the aspects of delight and value enhancers * Giving one Honda cart in free in large villages and in big town give one Honda cart per free per 5 km sq feet area to goods carrier * Reduce pollutants as compared to 3 wheeler from 21 % to 40% Market scenario: TATA ACE has captured 65% of the small commercial vechile segment Target Segment: The target segment are those who want to upgrade from these three wheelers and one who carry/ upload tons of goods How to cite Dabur Brand Revie, Papers
Sunday, April 26, 2020
Thalassemia Bangladesh Perspecti free essay sample
What is Thalassemia? Thalassemia is an inherited blood disorder in which parents pass the genes for disorder on to their children. It reduces reproduction of red blood cells in human body. In thalassemia patient, the genes that control globin production are mutated or deleted. As a result, formation of the corresponding globin chains is trimmed down and an abnormal hemoglobin ratio is enhanced. This abnormal ratio leads to a decreased synthesis of hemoglobin and expression of thalassemia. Professor Dr. Mamun Ahmed from the Department of Biochemistry and Molecular Biology, Dhaka University explained, ââ¬Å"If one among 23 pairs of chromosomes of oneââ¬â¢s body is affected by Alpha or Beta chain mutation, one may become victim of Thalassemia. If both the chromosomes of a pair are affected, chance is 25 percent that the person will be victim of this lethal disease. â⬠Thalassemia causes mutation in the DNA of cells that make hemoglobin, the substance in the red blood cells that carries oxygen throughout the body. We will write a custom essay sample on Thalassemia: Bangladesh Perspecti or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page The mutations thus disrupt the normal production of hemoglobin and cause low hemoglobin levels and a high rate of red blood cell destruction, causing anemia. Due to anemia, the blood does not have enough red blood cells to carry oxygen to the tissues, leaving one fatigued. Epidemiology Generally, thalassemia is prevalent in the people living in humid climate zones where malaria was endemic in the past or still exists. Since thalassemia acts as an antidote to malaria because of the blood cells easy degradation, it got epidemic in those regions. Thalassemia was first detected among Mediterranean inhabitants. In fact, this geographical association is responsible for its naming: Thalassa is Greek for the sea, Haema is Greek for blood. In Europe, the highest concentrations of the disease are found in Greece, coastal regions of Turkey, Southern Italy and the lower Po valley. The major Mediterranean islands (except the Balearics) such as Sicily, Sardinia, Malta, Corsica, Cyprus, and Crete are heavily affected in particular. High rate of thalassemia is also seen among other Mediterranean people, as well as those in the vicinity of the Mediterranean, including people from West Asia and North Africa. Far from the Mediterranean, South Asians are also affected. The Maldives has the highest incidence of Thalassemia in the world with a carrier rate of 18% of the population. Likewise, lots of people from Bangladesh, China, India, Malaysia and Pakistan are also believed to be thalassemia carriers. Descendants of people from Latin America and Mediterranean countries are other notable thalassemia carriers. Furthermore, a very low prevalence has been reported from people in Northern Europe (0. 1%) and Africa (0. 9%), with those in North Africa having the highest frequency. Types of Thalassemia Normal hemoglobin, known as hemoglobin A, has four protein chains ââ¬â two Alpha globins and two Beta globins. The two major types of thalassemia, Alpha and Beta, are named after defects in these protein chains. Both Alpha and Beta thalassemias include the following two forms: * Thalassemia major * Thalassemia minor Thalassemia major occurs as a result of inheritance of defective gene from both parents, while thalassemia minor occurs if the defective gene is received from only one parent. Persons with the minor form of the disorder are carriers of the disease and usually do not have symptoms. Alpha Thalassemia Four genes (two from each of the parents) are involved in making the Alpha hemoglobin chain. Alpha thalassemia trait occurs if one or two of the four genes are deleted or mutated. Four possible cases of Alpha thalassemia can be observed. * One mutated gene: There will be no signs or symptoms of thalassemia. However, there is always a risk of passing this disease to the predecessors. * Two mutated genes: It may cause mild anemia. This condition is called Alpha thalassemia minor. * Three mutated genes: Signs and symptoms will be moderate to severe. This condition is also called hemoglobin H disease. * Four mutated genes: This condition is called Alpha thalassemia major or hydrops fetalis. It usually causes a fetus to die before delivery or a newborn to die shortly after birth. Beta Thalassemia Two genes (one from each parent) are needed to make enough Beta globin protein chains. Beta thalassemia occurs if one or both genes are altered. The severity of Beta thalassemia depends on the amount of affected genes. Two possible cases of Alpha thalassemia can be observed. * One mutated ene: Signs and symptoms will be mild. This condition is called Beta thalassemia minor. * Two mutated genes: Moderate to severe anemia will be experienced. This condition is called Beta thalassemia major or Cooleys anemia. Babies born with two defective Beta hemoglobin genes usually are healthy at birth, but develop signs and symptoms within the first two years of life. Risk Factors Family history and ancestry are the two risk factors for thalassemia. Fam ily History: Thalassemias are inherited. They are passed from parents to children through the genes. If you have a family history of thalassemia, you may have an increased risk of the condition. Ancestry: Thalassemia occurs most often in people of Italian, Greek, Middle Eastern, South Asian and North African ethnicity. Symptoms Signs and symptoms of thalassemia include: * Fatigue. * Weakness. * Shortness of breath. * Pale appearance. * Irritability. * Yellow discoloration of skin (jaundice). * Facial bone deformities. * Slow growth. * Abdominal swelling. * Dark urine. The signs and symptoms depend on the type and severity of thalassemia. Some babies show signs and symptoms at birth, while others may develop signs or symptoms during the first two years of life. People with one affected hemoglobin gene usually do not experience any thalassemia symptom. Complications Possible complications of thalassemia include: * Iron overload: People with thalassemia can get too much iron in their bodies, either from the disease itself or from frequent blood transfusions, which can damage the heart, liver and endocrine system. * Infection: People with thalassemia have an increased risk of infection, especially if spleen is removed. In cases of severe thalassemia, the following complications may occur: * Bone deformities: Thalassemia may expand bone marrow, which causes the bones to widen. This often results in abnormal bone structure, especially in the face and skull. Bone marrow expansion also makes bones thin and brittle, increasing the chance of broken bones. * Enlarged spleen: The spleen helps the body to fight infection and filter unwanted material, such as old or damaged blood cells. Thalassemia is often accompanied by the destruction of a large number of red blood cells, making the spleen work harder than normal, causing it to enlarge. It can aggravate anemia and reduce the life span of transfused red blood cells. If the spleen grows too big, it may need to be removed. * Slowed growth rates: Anemia can cause a childs growth to slow. Puberty also may be delayed in children with thalassemia. * Heart problems: Heart problems, such as congestive heart failure and abnormal heart rhythms, may be associated with severe thalassemia. Diagnosis Doctors diagnose thalassemia using blood tests, including a complete blood count (CBC) and special hemoglobin tests. CBC provides information about the amount of hemoglobin and different blood cells in a sample of blood. A thalassemia patient has fewer healthy red blood cells and less hemoglobin than normal in blood. * Hemoglobin tests measure the types of hemoglobin in a blood sample. One, who has thalassemia, has problems with the Alpha or Beta globin protein chains of hemoglobin. Doctors also test the amount of iron in the blood to find out whether the anemia is due to iron deficie ncy or thalassemia. Iron-deficiency anemia occurs if the body doesnt have enough iron to make hemoglobin. However, thalassemia induced anemia occurs because of the problem with either the alpha globin or beta globin chain of hemoglobin, not because of lack of iron. Since thalassemia is passed from generation to generation through genes, family genetic studies can also help to diagnose the disorder. These studies involve taking a family medical history and doing blood tests on family members. The tests will show whether any family members have missing or altered hemoglobin genes. Once identified, the risk of passing the disorder to a specific predecessor can be determined. If you and your spouse ââ¬â both are thalassemia carriers, you should consider prenatal testing whenever you are expecting a baby. Prenatal testing involves taking a sample of amniotic fluid or tissue from the placenta (Amniotic fluid is the fluid in the sac surrounding a growing embryo and placenta is the organ that attaches the umbilical cord to the mothers womb). Tests will reveal if your baby will have thalassemia or not and if yes, how severe it may be. ââ¬Å"If prenatal diagnosis shows that the baby would be victim of this lethal disease, abortion of the baby may require to be doneâ⬠, Dr. Mamun Ahmed suggested. Treatment Treatment varies with the type and the severity of the disease. Treatment for mild thalassemia: Occasionally, a blood transfusion may be needed, particularly after a surgery or after having a baby. Treatment for moderate to severe thalassemia: Treatments for moderate to severe thalassemia may include: * Stem cell or bone marrow transplant: It is used to treat severe thalassemia in some particular cases. Prior to a stem cell transplant, very high doses of drugs or radiation to destroy the diseased bone marrow are applied. Then infusions of stem cells are received from a compatible donor. However, this treatment is undertaken in most severe cases when there is a well-matched donor available ââ¬â usually a sibling, because these procedures have serious risks, including death. Nevertheless, very high cost of the treatment has kept this procedure limited only to a handful of patients. * Frequent blood transfusions: Frequent blood transfusions are often required, possibly every few weeks. Over the time, blood transfusions cause a buildup of iron in the blood, which can damage heart, liver and other organs. To help the body get rid of the extra iron, medications are required. Iron overload is the single most expensive part of the blood transfusion dependant treatment of thalassemia. Most common therapy for iron chelation is subcutaneous injection of ââ¬Ëdeferrioxamineââ¬â¢, commonly known as ââ¬Ëdesferalââ¬â¢, with a micro pump over a period of 10 to 12 hours. Ideally the injection needs to be taken every day. But, for practical reasons it is administered 5 or 6 days a week. The therapy is painful and very expensive. ââ¬ËDeferiproneââ¬â¢ is a cheaper alternate to ââ¬Ëdesferalââ¬â¢ and it is taken orally. However, its unfortunate severe side effects make it the second choice for iron chelation therapy. * Splenectomy: It is another form of treatment. When the spleen becomes too active and starts destroying red blood cells, transfusion becomes less effective with time being. Then it may become necessary to take the spleen out. This operation is called splenectomy. Prevention All forms of thalassemia are transmitted only through hereditary. It is a severe and incurable disease so emphasis must shift from treatment of the affected child to prevention of such births in future. Living with Thalassemia With the advancements in medical science and technology, survival and quality of life have improved for thalassemia affected people. Living with thalassemia can be challenging, but several approaches can help you cope. If you are a thalassemia carrier, be sure to: * Avoid excess iron. Unless your doctor recommends it, dont take vitamins or other supplements that contain iron. * Eat a healthy balanced diet with adequate calcium and vitamin D to boost your energy and keep your bones healthy. Your doctor may also recommend you to take a folic acid supplement to help your body make new red blood cells. Avoid infections. Protect yourself from infections with frequent hand-washing and by avoiding ailing people. This is especially important if you have your spleen removed. * Follow your treatment plan. * Get ongoing medical care. * Seek help and support. Thalassemia in Bangladesh Bangladesh is one of the most thalassemia prone countries of the world. It is a matter of grief that there is no definite data regarding the carrier status of hereditary hemoglobin disorder, existing in Bangladesh. No screening program had ever been taken in any population group. In 2002, a World Health Organization (WHO) report concerning Bangladesh estimated that about 3 percent of the total population was carrying Beta thalassemia while 4 percent were carriers of abnormal hemoglobin E (HbE). Hence, there were about 3. 6 millions carriers of Beta thalassemia and 4. 8 millions carriers of HbE. It also stated that Beta thalassemia and abnormal HbE affected birth per thousand were 0. 106 and 3. 0 respectively. In 2004, Dhaka Shishu Hospital conducted a preliminary study to identify carrier state among the school children. The study revealed that 4. 1 and 6. percent children were carrier of Beta thalassemia HbE respectively. In tribal school children, the prevalence of the HbE trait was 41. 1 percent, while that of Beta thalassemia was 4. 2 percent. The study also concluded that the expected births of Beta thalassemia affected children were about 1,040 per year, with a further 6,443 HbE affected births. Thus more than 7,000 children are born with thalassemia ea ch year in Bangladesh. Thalassemia Treatment in Bangladesh Dhaka Shishu Hospital was the pioneer in establishing a separate specialized center for care and treatment of thalassemic children. This center now has 17 beds for giving transfusion to thalassemic children. It provides free treatment to poor thalassemic children providing them with free blood and ââ¬Ëdesferalââ¬â¢ onà requirement basis. The center has its own blood bank ensuring safe blood and laboratory for diagnosing thalassemia and also other investigations relevant to this disease. There are two genetic counselors for giving advice to carriers and parents of thalassemic children. This center has also doing research work on thalassemia and has published many papers in local journals. In 2004, another specialized thalassemia treatment centre named Bangladesh Thalassemia Hospital, established by Bangladesh Thalassemia Society, launched their journey. It has developed facilities to serve 30 patients at a time. With foreign assistance, it has established a blood bank, equipped with modern instruments, for preservation of blood. It also has a diagnostic unit as well as a unit for iron chelation therapy. ASHA Thalassemia Center, founded by Bangladesh Thalassemia Foundation in May 2008, is another addition to the existing thalassemia treatment facilities. It consists of 8 beds with capacity of giving 16 transfusions a day in two sifts. There are 5 employees for this center including a doctor and a nurse. The patients get day care blood transfusion, iron chelation, medical consultation and counseling plus essential laboratory tests here. In August 2009 Nobel laureate Dr. Muhammad Yunus, the then chairman of Grameen Health Care Trust and Cure2Children Foundation of Italyà signed an memorandum of understanding to establish a bone marrowà transplantation centre for thalassemia in Bangladesh. A committee of Grameen Health Care Trust, Cure2Children, thalassemia associations and local rofessionals prepared an action plan to perform feasibility study with the first transplant within the first half of 2010 and a plan to cure all uses of Thalassemia by 2025. Conclusion With global improvement in prevention and treatment of childhood diseases to prevent mortality from malnutrition, diarrhea and acute respiratory infections, thalassemia wil l become a major issue in developing countries like Bangladesh in this millennium. All over the world efforts are being made to prevent the birth of thalassemic child and to improve the quality of the patientââ¬â¢s life. Thalassemia needs to be recognized, as an important health issue in this country and steps need to be taken to control the birth of thalassemic children. The following steps to be recommended: * Social awareness: It is of prime importance to create awareness about thalassemia to the general population by holding seminars, workshops and writing articles in the daily newspapers, broadcasting in television and radio. Thalassemia day is observed on 8 May all over the world. On this day various activities has to be arranged and media should play a vital role here for dissemination of information and recent advancements about thalassemia. The government must also take steps to create awareness among the rural populations by involving thana health complexes and other different local organizations. Apropos, it is a matter of sorrow that no other city in Bangladesh other than Dhaka has facilities for the diagnosis of thalassemia. * Population screening: Due to huge population, it is reasonable to select a cohort for screening e. g. pregnant women. They are usually accessible to the health system and information on reproductive risk is of immediate relevance to them. Screening of close relatives of some of the affected children also is insisted. * Genetic counseling: Thalassemia carriers and parents having a thalassemic child should be facilitated with genetic counseling. It should be non directive and the counselorââ¬â¢s main role is to provide people at risk with full information, give them time for consideration and support them in making decisions. * Prenatal diagnosis: It is a well established procedure in developed countries. There is need for religious and legal scrutiny of prenatal diagnosis and therapeutic abortion in our society. ve
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